雷公藤甲素 Triptolide(TPL) CAS:38748-32-2 C12310

Triptolide(TPL)

雷公藤甲素; 雷公藤内酯醇; 雷公藤多甙

Product Name:Triptolide(TPL)
 
CAS No.:38748-32-2
 
Synonym:(-)-Triptolide;Triptolid;NSC 163062;PG 490
 
Chemical name:Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
 
Molecular formula:C20H24O6
 
Molecular weight:360.40
  
Purity(HPLC):≥98%

Biological Activity:

A potent naturally occuring immunosupressant and anti-inflammatory terpenoid. Induces apoptotic death in T lymphocytes and tumor cells. Inhibits T-cell IL-2 expression at the level of NF-κB transcriptional activation. Inhibits induction of MMP-3, MMP-13, and ADAMTS-4 in cell culture.

CAS No.	Product Name
34157-83-0	Celastrol(Tripterin); tripterine; (2R,4aS,6aS,6aR,14aS,14bR)-10-Hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid; 3-Hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid; 3-Hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic Acid; NSC70931; 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid
1258-84-0	Pristimerin(NSC 99281);(9b,13a,14b,20a)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tertraen-29-oic acid methyl ester; Celastrol methyl ester; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid methyl ester; 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, methyl ester
38748-32-2	Triptolide(TPL);PG490 ; PG 490 ; PG-490;(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
38647-10-8	Tripdiolide;Triptodiolide
37239-51-3	Wilfordine;Wilfordin;(8R,9R,10R,11S,12S,13R,14R,15S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-18,21-dihydroxy-8,18,21-trimethyl-,8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione;8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione,10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-18,21-dihydroxy-8,18,21-trimethyl-,(8R,9R,10R,11S,12S,13R,14R,15S,21S,22S,23R)-
37239-47-7	Wilforgine;Wilforgin; Evonimine, 8-(acetyloxy)-O2-deacetyl-8-deoxo-O2-(3-furanylcarbonyl)-, (8α)-;3-Furancarboxylic acid, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-;(8alpha)-8-(Acetyloxy)-O2-deacetyl-8-deoxo-O2-(3-furanylcarbonyl)- evonimine Wilforgin; 3-Furancarboxylic acid (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester;AIDS088959; AIDS-088959;BRN 0078231; Evonimine, 8-(acetyloxy)-O(sup 2)-deacetyl-8-deoxo-O(sup 2)-(3-furanylcarbonyl)-, (8-alpha)-
11088-09-8	Wilforine;26-Deoxywilfordine; Evonimine, 8-(acetyloxy)-O2-benzoyl-O2-deacetyl-8-deoxo-, (8α)-;8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-;(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione
37239-48-8	Wilfortrine;Wilfortrin;3-Furancarboxylic acid,(8R,9R,10R,11S,12R,13R,14R,15S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-18,21-dihydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-ylester
345954-00-9	Wilfornine A;8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,14,22,23-pentakis(acetyloxy)-12-[(acetyloxy)methyl]-18-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12R,13R,14R,15S,21S,22S,23R)-
168009-85-6	Triptonine B; Triptonine B (Tripterygium wilfordii); (-)-Triptonine B; 18-O-(3-Furoyl)wilfortrine; Wilfortrine 26-(3-furoate); 3-Furancarboxylic acid, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H[1,9]dioxacyclooctadecino[4,3-b]pyridine-14,18-diylester, (8R,9R,10R,11S,12R,13R,14R,15S,18R,21S,22S,23R)-
84104-71-2	Wilforlide A
38647-11-9	Triptonide;(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione;NSC 165677;  PG 492
107316-88-1	Demethylzeylasteral; (9beta,13alpha,14beta,20alpha)-2,3-Dihydroxy-9,13-dimethyl-6,23-dioxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic acid
74285-86-2	Triptophenolide;(+)-Triptophenolide; Hypolide; (3bR,9bS)-3b,4,5,9b,10,11-Hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)phenanthro[1,2-c]furan-1(3H)-one
61276-17-3	Acteoside;Verbascoside;[(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate;Kusaginin; Russetinol; Stereospermin; TJC 160; NSC 603831; β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
61303-13-7	Isoacteoside; Isoverbascoside; [(2R,3R,4S,5R,6R)-5-(3,4-Dihydroxyphenyl)-6-ethoxy-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
989-51-5	(-)-Epigallocatechin gallate (EGCG);(2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate); (-)-Epigallocatechin gallate 3-O-gallate;(-)-Epigallocatechin Gallate
62284-79-1	(-)-p-Bromotetramisole oxalate;L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate; (-)-p-Bromolevamisole oxalate
N/A	(1S,3R,5R)-PIM447 dihydrochloride; (1S,3R,5R)-LGH447 dihydrochloride
1820565-69-2	PIM-447 dihydrochloride;LGH-447 dihydrochloride;N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide
1210608-43-7	PIM447;LGH447; PIM-447; LGH-447; PIM 447; LGH 447
30636-90-9	(20S)-Protopanaxadiol; 20-Epiprotopanaxadiol; 20(S)-APPD
N/A	(Ac)Phe-Lys(Alloc)-PABC-PNP
334-49-6	(E)-2-Decenoic acid; trans-2-Decenoic acid;trans-2-Decylenic Acid;(E)-dec-2-enoic acid
15790-91-7	(Z)-2-Decenoic acid; cis-2-Decenoic acid;(Z)-dec-2-enoic acid
878006-06-5	(E)-[6]-Dehydroparadol
27113-22-0	Paradol;[6]-Gingerone;  [6]-Paradol;Heptyl 4-hydroxy-3-methoxyphenethyl ketone
19685-09-7	(S)-10-Hydroxycamptothecin; 10-HCPT; 10-Hydroxycamptothecin;(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 10-Hydroxycamptothecine; NSC 107124
150145-89-4	(S)-MCPG;(+)-MCPG;(S)-α-Methyl-4-carboxyphenylglycine;4-[(1S)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate; 4-[(1S)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate; 4-[(1S)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate;(alphaS)-alpha-Amino-4-Carboxy-alpha-Methyl-Benzeneacetic Acid
146669-29-6	(RS)-MCPG;(±)-MCPG;(RS)-α-Methyl-4-carboxyphenylglycine;4-[(1R)-1-Azaniumyl-1-Methyl-2-Oxido-2-Oxo-Ethyl]Benzoate; 4-[(1R)-1-Ammonio-1-Methyl-2-Oxido-2-Oxoethyl]Benzoate; 4-[(1R)-1-Ammonio-2-Keto-1-Methyl-2-Oxido-Ethyl]Benzoate;alpha-Amino-4-Carboxy-alpha-Methyl-Benzeneacetic Acid
1189561-66-7	(S)-Gossypol acetic acid;(S)-(+)-Gossypol acetic acid
866541-93-7	AT-101 acetic acid;(R)-(-)-Gossypol acetic acid; (-)-Gossypol acetic acid; (R)-Gossypol acetic acid;(R)-Gossypol acetic acid
90141-22-3	AT-101;(R)-(-)-Gossypol; R-(-)-gossypol acetic acid; AT 101; AT101;(-)-Gossypol;(R)-Gossypol; (R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde
66389-74-0	(+)-Apogossypol; Apogossypol;  NSC736630
287194-41-6	(+)-DHMEQ;(1R,2R,6R)-Dehydroxymethylepoxyquinomicin; (1R,2R,6R)-DHMEQ
287194-40-5	(-)-DHMEQ;Dehydroxymethylepoxyquinomicin;Dehydroxymethylepoxyquinomicin (DHMEQ)
287194-38-1	DHMEQ racemate;rel-DHMEQ
221243-82-9	1-Naphthyl PP1;1-NA-PP 1; 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
956025-47-1	1-Naphthyl PP1 hydrochloride;1-NA-PP 1 hydrochloride
221244-14-0	1-NM-PP1; PP1 Analog II; 1-NM-PP 1;1 NM-PP1; 4-Amino-1-tert-butyl-3-(1'-naphthylmethyl)pyrazolo[3,4-d]pyrimidine
32981-86-5(92999-93-4)	10-Deacetyl Baccatin III (10-DAB III);10-Deacetylbaccatin III; 10-Deacetylbaccatine III;10 DAB III;10-DAB;12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one
167074-97-7	10-Oxo Docetaxel;Docetaxel Impurity
403811-55-2	10058-F4;10058F4;5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
1430089-64-7	2,4-Pyrimidinediamine with linker;N2-[4-[(3-Aminopropyl)amino]phenyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine
163042-96-4	2-Cl-IB-MECA; Chloro-IB-MECA; CF-102; CI-IB-MECA;1-[2-Chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-beta-D-ribofuranuronamide;2-Chloro-N6-(3-iodobenzyl)adenosine-5'-N-methyluronamide
154-17-6	2-Deoxy-D-glucose;2-Deoxy-D-arabino-hexose;  D-Arabino-2-deoxyhexose;2-Deoxyglucose;(4R,5S,6R)-6-(hydroxymethyl)oxane-2,4,5-triol
362-07-2	2-Methoxyestradiol; 2-ME2; NSC-659853
85999-40-2	23-Hydroxybetulinic acid;Anemosapogenin;3beta,23-Dihydroxylup-20(29)-en-28-oic acid
180288-69-1	Anti HER2, Ig gamma-1 chain C region;Recombinant humanized anti-HER2 antibody;Trastuzumab;RhuMab HER2
205923-56-4	C 225; EGFR antibody; IMC 225; IMC-C 225;Cetuximab
185243-69-0	rhu-TNFR-Fc; Etanercept;rhuTNFR: Fc
1968-05-4	3,3'-Diindolylmethane;DIM; 3,3'-Methylenebisindole
1113-59-3	3-Bromopyruvic acid;Bromopyruvic acid; Hexokinase II Inhibitor II, 3-BP
5142-23-4	3-Methyladenine(3-MA); 6-Amino-3-methylpurine;3-Methyl-6-aminopurine; N3-Methyladenine; NSC 66389
794458-56-3	360A;3,3'-[2,6-Pyridinediylbis(carbonylimino)]bis[1-methylquinolinium]
737763-37-0	360A iodide;360 A iodide;3,3'-[2,6-Pyridinediylbis(carbonylimino)]bis[1-methylquinolinium] diiodide
28755-03-5	3CAI; 3 CAI; 3-CAI; 2-Chloro-1-(3-Indolyl)-Ethanone
18550-98-6	3PO;3PO (inhibitor of glucose metabolism)
68047-06-3	4-Hydroxytamoxifen;(Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen;(Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol
155798-08-6	4-IBP;4 IBP; 4IBP;N-(N-Benzylpiperidin-4-yl)-4-iodobenzamide
328998-25-0	4E1RCat; 4-[2,3-Dihydro-3-[[5-(4-nitrophenyl)-2-furanyl]methylene]-2-oxo-5-phenyl-1H-pyrrol-1-yl]benzoic acid;4-[(3E)-3-[[5-(4-Nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl]benzoic acid
315706-13-9	4EGI-1; alpha-[2-[4-(3,4-Dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitrobenzenepropanoic acid; α-[2-[4-(3,4-Dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-benzenepropanoic acid
218916-52-0	5,15-Diacetyl-3-benzoyllathyrol; (1aR,2E,4aR,6S,7S,7aR,8R,11aS)-4a,8-Bis(acetyloxy)-7-(benzoyloxy)-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-9-methylene-4H-cyclopenta[a]cyclopropa[f]cycloundecen-4-one; Diacetyl Benzoyl Lathyrol; Euphorbia factor L3; Phytoclear EL-1
320-67-2	Azacitidine(5-Azacytidine);Ladakamycin; 5-AzaC;4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazine-2(1H)-one
51-21-8	5-Fluorouracil(5-FU);5-Fluoro-2,4(1H,3H)-pyrimidinedione; 5-Fluoro-2,4-pyrimidinedione; 5-Fluoropyrimidine-2,4-dione
24386-93-4	5-Iodotubercidin;5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine;7-Deaza-7-iodoadenosine;NSC 113939;  5-Itu
484-20-8	5-Methoxypsoralen;Bergapten;4-Methoxy-7H-furo[3,2-g]chromen-7-one;8-Demethoxyisoimpinellin;  Bergaptan; Bergaptene; Geralen; Heraclin; Majudin; NSC 95437; Psoraderm