Anti-C1GALT1/FITC抗体 Anti-C1GALT1/FITC

Anti-C1GALT1/FITC抗体

产品编号YB-9685R-FITC

英文名称Anti-C1GALT1/FITC

中文名称FITC标记的N-乙酰半乳糖胺糖蛋白3、β-半乳糖转移酶1抗体

别    名B3Gal T8; Beta 1 3 galactosyltransferase; C1GALT; Core 1 beta1 3 galactosyltransferase 1; Core 1 beta3 Gal T; Core 1 O glycan T synthase; Core 1 synthase glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1 3 galactosyltransferase; Glycoprotein N acetylgalactosamine 3 beta galactosyltransferase 1; T synthase.

Anti-C1GALT1/FITC抗体

说 明 书100ul  

研究领域心血管  细胞生物  **学  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量40kDa

细胞定位细胞膜

Anti-C1GALT1/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

*** 原KLH conjugated synthetic peptide derived from human C1GALT1

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-C1GALT1/FITC抗体

产品介绍background:

C1GALT1 is a glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is synthesized by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended O-glycans in glycoproteins. C1GALT1 plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.

Function:

Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.

Subunit:

Homodimer; disulfide-linked (By similarity).Anti-C1GALT1/FITC抗体 Interacts with the C1GALT1C1 chaperone; required for galactosyltransferase activity.

Subcellular Location:

Membrane.

Tissue Specificity:

Widely expressed. Highly expressed in kidney, heart, placenta and liver.

Similarity:

Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.

Database links:

Entrez Gene: 56913 Human

Omim: 610555 Human

SwissProt: Q9NS00 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.