Anti-CHURC1/FITC抗体 Anti-CHURC1/FITC
产品简介
Anti-CHURC1/FITC抗体和抗原之间的结合具有高度的特异性,**组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,Anti-CHURC1/FITC抗体通过**动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。
产品详细信息
Anti-CHURC1/FITC抗体
产品编号YB-11820R-FITC
英文名称Anti-CHURC1/FITC
中文名称FITC标记的神经诱导胚胎发育相关蛋白Churchill抗体
别 名CHURC-1; C14orf52; CHCH; CHURC 1; Churchill domain containing 1; FLJ33064; My015; Protein Churchill; CHUR_HUMAN.
Anti-CHURC1/FITC抗体
说 明 书100ul
研究领域细胞生物 发育生物学 神经生物学 信号转导 生长因子和** 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Dog, Cow, Horse, Rabbit, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量13kDa
Anti-CHURC1/FITC抗体性 状Lyophilized or Liquid
浓 度1mg/ml
*** 原KLH conjugated synthetic peptide derived from human CHURC1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-CHURC1/FITC抗体
产品介绍background:
CHURC1 is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.
Function:
CHURC 1 belongs to the Churchill family. It is a transcriptional activator that mediates FGF signaling during neural development. It plays a role in the regulation of cell movement, but does not bind DNA by itself. There are two named isoforms.
Anti-CHURC1/FITC抗体Similarity:
Belongs to the Churchill family.
Database links:
UniProtKB/Swiss-Prot: Q8WUH1.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.