Anti-C17orf87/FITC抗体 Anti-C17orf87/FITC

Anti-C17orf87/FITC抗体

产品编号YB-13685R-FITC

英文名称Anti-C17orf87/FITC

中文名称FITC标记的第十七号染色体开放阅读框87抗体

别    名C17orf87; SCIMP_HUMAN; DTFT5783; SCIMP; SLP adaptor and CSK interacting membrane protein; SLP65/SLP76; Transmembrane protein C17orf87; UNQ5783; UNQ5783/PRO16090.

Anti-C17orf87/FITC抗体

说 明 书100ul  

研究领域肿瘤  细胞生物  **学  信号转导  细胞类型标志物  跨膜蛋白  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量17kDa

Anti-C17orf87/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

*** 原KLH conjugated synthetic peptide derived from human C17orf87

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-C17orf87/FITC抗体

产品介绍background:

C17orf87 (chromosome 17 open reading frame 87) is a 145 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Anti-C17orf87/FITC抗体Subcellular Location:

Membrane.

Database links:

Entrez Gene: 388325 Human

SwissProt: Q6UWF3 Human

Unigene: 462080 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.