吲哚胺N-甲基转移酶抗体 INMT
产品简介
吲哚胺N-甲基转移酶抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。吲哚胺N-甲基转移酶抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
产品详细信息
吲哚胺N-甲基转移酶抗体
规格:1mg/1ml
英文名: INMT
别名: Amine N methyltransferase; Amine N-methyltransferase; Aromatic alkylamine N methyltransferase; Aromatic alkylamine N-methyltransferase; Arylamine N methyltransferase; Arylamine N-methyltransferase; In
分子量: 29kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human INMT
交叉反应:Human, Orangutan
细胞定位:细胞浆
吲哚胺N-甲基转移酶抗体产品介绍:background: Methylation is an important reaction in the metabolism of many drugs, other xenobiotics and endogenous molecules. A methyltransferase is a type of transferase enzyme that transfers a methyl group from a donor to an acceptor. INMT (indolethylamine N-methyltransferase), also known as Temt or aromatic alkylamine N-methyltransferase, is a 264 amino acid protein belonging to the NNMT/PNMT/TEMT family. Localized to the cytoplasm, INMT catalyzes the N-methylation of tryptamine and structurally related compounds. Existing as a monomer, INMT may have a role in the in vivo synthesis of psychoactive compounds or neurotoxins.吲哚胺N-甲基转移酶抗体 The gene encoding INMT maps to human chromosome 7p14.3 and mouse chromosome 6 B3. Function: Catalyzes the N-methylation of tryptamine and structurally related compounds. Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. The highest levels were in thyroid, adrenal gland, ***** and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in ***** and fetal kidney and liver, in ***** spleen, thymus, ovary, colon and bone marrow.吲哚胺N-甲基转移酶抗体 Not expressed in peripheral blood leukocytes and brain. Similarity: Belongs to the NNMT/PNMT/TEMT family. Gene ID: 11185 Database links: Entrez Gene: 11185 Human Omim: 604854 Human SwissProt: O95050 Human Unigene: 632629 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
吲哚胺N-甲基转移酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 新陈代谢 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid