组蛋白去乙酰化酶复合亚基SAP30抗体 SAP30
产品简介
组蛋白去乙酰化酶复合亚基SAP30抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。组蛋白去乙酰化酶复合亚基SAP30抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
产品详细信息
组蛋白去乙酰化酶复合亚基SAP30抗体
规格:1mg/1ml
英文名: SAP30
别名: 30 kDa Sin3-associated polypeptide; Histone deacetyla******plex subunit SAP 30; Histone deacetyla******plex subunit SAP30; MSin3A associated polypeptide p30; SAP 30; Sap30; SAP30_HUMAN; Sin3 associate
分子量: 23kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SAP30
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Guinea Pig, Cat, Spider Monkey
细胞定位:细胞核
组蛋白去乙酰化酶复合亚基SAP30抗体产品介绍:background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetyla******plex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Jul 2008] Function: Involved in the functional recruitment of the Sin3-histone deacetyla******plex组蛋白去乙酰化酶复合亚基SAP30抗体 (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. Subcellular Location: Nucleus. Tissue Specificity: Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus; lowest levels in brain,组蛋白去乙酰化酶复合亚基SAP30抗体 placenta, lung and kidney. Similarity: Belongs to the SAP30 family. Database links: Entrez Gene: 8819 Human Entrez Gene: 60406 Mouse Omim: 603378 Human SwissProt: O75446 Human SwissProt: O88574 Mouse Unigene: 591715 Human Unigene: 118 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组蛋白去乙酰化酶复合亚基SAP30抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid