桥粒芯糖蛋白1 Desmoglein 1

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产品价格： < 面议

产品型号：Desmoglein 1

品牌：单克隆抗体/多克隆抗体

公司名称：上海信裕生物技术有限公司

所在地：上海松江

浏览次数：116 次

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产品简介

桥粒芯糖蛋白1应用于IHC、WB、 IF、IP、ELISA等科研实验，按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源，可将其分为天然抗体和**抗体。桥粒芯糖蛋白1生产每个流程都执行严格的检测标准，保证蛋白抗原产品质量，质量稳定，实验效果明显。

产品详细信息

桥粒芯糖蛋白1

规格：1mg/1ml

英文名： Desmoglein 1

别名： Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal Glycoprotein 1; DG1; DGI; DSG; DSG1; DSG1_HUMAN; Pemphigus Foliaceus Antigen; PPKS1; SPPK1.

分子量： 108kDa

储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型：Polyclonal

亚型：IgG

纯化方法：affinity purified by Protein A

**原：KLH conjugated synthetic peptide derived from human Desmogle

交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

细胞定位：细胞膜

桥粒芯糖蛋白1产品介绍：background: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger. Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Subunit: 桥粒芯糖蛋白1Binds to JUP/plakoglobin. Subcellular Location: Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, desmosome. Tissue Specificity: Epidermis, tongue, tonsil and esophagus. DISEASE: Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by 桥粒芯糖蛋白1thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger. Similarity: Contains 4 cadherin domains. Database links: UniProtKB/Swiss-Prot: Q02413.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

桥粒芯糖蛋白1产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域：细胞生物信号转导转录调节因子细胞粘附分子

储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源： Rabbit

外观： Lyophilized or Liquid