神经元素1抗体 Neurogenin 1
产品简介
神经元素1抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。神经元素1抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产品质量,质量稳定,实验效果明显。
产品详细信息
神经元素1抗体
规格:1mg/1ml
英文名: Neurogenin 1
别名: AKA; Ath4c; bHLHa6; Class A basic helix-loop-helix protein 6; Helix loop helix protein mATH 4C; MATH4C; NeuroD3; Neurog 1; Neurog1; Neurogenic basic helix loop helix protein; Neurogenic basic-helix-lo
分子量: 26kD
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NGN1/Neu
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位:细胞核
神经元素1抗体产品介绍:background: The neurogenin family of proteins belongs to the basic helix-loop-helix (bHLH) superfamily and consists of neurogenin 1, neurogenin 2 and neurogenin 3 (also designated ngn3). bHLH members are transcriptional regulators that determine cell fate. During mouse neurogenesis, Neurogenin 1 and Neurogenin 2 are expressed in distinct progenitor populations in the central and peripheral nervous systems. Targeted mutation analyses have shown that Neurogenin 1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia and that Neurogenin 2 is essential for the determination of precursors for epibranchial placode-derived 神经元素1抗体sensory neurons. The gene which encodes Neurogenin 1 maps to human chromosome 5q23-q31. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Subcellular Location: Nucleus. Tissue Specificity: Expression restricted to the embryonic 神经元素1抗体nervous system. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Database links: UniProtKB/Swiss-Prot: Q92886.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产神经元素1抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 干细胞 细胞类型标志物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid