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- 产品名称：Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体
- 产品型号：Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2016-05-09
- 在线询价
简单介绍
Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)
Cat. Number:
Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体XY-5193R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 beingAnti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体 approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.
Also known as:
phospho-AKT1/AKT2/AKT3 (Tyr315+Tyr316+Tyr312); Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体AKT1/AKT2/AKT3(phospho-Tyr315/316/312); AKT1/2/3 (phospho Y315 + Y316 + Y312); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; AKT 2; AKT2; AKT-2; AKT2_HUMAN; AKT 3; AKT3; AKT-3; AKT3_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PKB beta; PKB gamma; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Tyr315.
●
Predicted Molecular Weight: 56kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions Anti-phospho-AKT1+AKT2+AKT3 (Tyr315+316+312)抗体must be determined by the end user.
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