Anti-ARS2抗体

Cat. Number:

Anti-ARS2抗体KL-7970R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ARS2(Arsenite resistanceAnti-ARS2抗体 protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the Anti-ARS2抗体genotoxicity and carcinogenicity of arsenite.

Also known as:

ARS2 protein; Arsenate resistance protein ARS2; Arsenite resistance protein 2; Arsenite resistance protein; ASR2; MGC126427; Anti-ARS2抗体Serrate; Serrate RNA effector molecule homolog (Arabidopsis); Serrate RNA effector molecule homolog; SRRT; SRRT_HUMAN.

Specificity:

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. Anti-ARS2抗体
Optimal working dilutions must be determined by the end user.