Anti-C3orf15抗体

Cat. Number:

Anti-C3orf15抗体KL-9823R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The c-Myc proto-oncogene plays a significant role in cell proliferation, differentiation, transformation and apoptosis. A novel Anti-C3orf15抗体c-Myc binding protein, MYCBP (also designated AMY-1), binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. MYCBP translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. MYCBP and AAT-1 (AMY-1-associating protein expressed in testis 1) have been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP and AAT-1 in spermatogenesis. Expression of the AAT-1 gene is regulated by two different promoters, which result in various isoforms. One promoter generates expression of the AAT-1, AAT-1å, AAT-1∫ and AAT-1© isoforms, which are specifically expressed in testis, whileAnti-C3orf15抗体 the other promoter generates AAT-1L, AAT-1M and AAT-1S, which are differentially expressed.

Also known as:

AAT 1; AAT-1; AAT1; Anti-C3orf15抗体AAT1 alpha; AAT1_HUMAN; AAT1alpha; AMY 1 associating protein expressed in testis 1; AMY-1-associating protein expressed in testis 1; Chromosome 3 open reading frame 15; MYCBP binding protein.

Specificity:

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200  IEM=1:20-200  IGS=1:20-200  GICA=1:20-200   
Not yet tested in other applications. 
Optimal working Anti-C3orf15抗体dilutions must be determined by the end user.