Anti-Acetoacetyl-CoA synthetase抗体

Cat. Number:

Anti-Acetoacetyl-CoA synthetase抗体KL-11383R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?targetAnti-Acetoacetyl-CoA synthetase抗体 gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

Also known as:

Acetoacetyl-CoA synthetase;Anti-Acetoacetyl-CoA synthetase抗体 ACSF1; AACS; Acyl-CoA synthetase family member 1; Protein sur-5 homolog; AACS_HUMAN.

Specificity:

Storage:

Shipped at 4℃, Store Anti-Acetoacetyl-CoA synthetase抗体at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working Anti-Acetoacetyl-CoA synthetase抗体dilutions must be determined by the end user.