Anti-phospho-AMPK alpha 2 (Ser176)抗体

Cat. Number:

Anti-phospho-AMPK alpha 2 (Ser176)抗体KL-12468R

Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in Anti-phospho-AMPK alpha 2 (Ser176)抗体regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

Also known as:

Anti-phospho-AMPK alpha 2 (Ser176)抗体AMPK alpha 2 (phospho S176); AMPK alpha 2 (phospho Ser176); p-AMPK alpha 2 (S176); p-AMPK alpha 2 (Ser176); p-AMPK2(phospho S176); 5'-AMP-activated protein kinase catalytic subunit alpha-2; AAPK2_HUMAN; AMP activated protein kinase alpha 2 catalytic subunit; AMPK 2; AMPK alpha 2 chain; AMPK subunit alpha-2; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 catalytic subunit.

Specificity:

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-phospho-AMPK alpha 2 (Ser176)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.