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- 产品名称:Anti-BRMS1抗体
- 产品型号:乳腺癌转移抑制基因1抗体
- 产品展商:KALANG
- 产品文档:无相关文档
- 发布时间:2016-05-12
- 在线询价
简单介绍
Anti-BRMS1抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-BRMS1抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-BRMS1
Cat. Number:
Anti-BRMS1抗体KL-1015R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Breast cancer metastasis-suppressor Anti-BRMS1抗体1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32Anti-BRMS1抗体 expression. This produces a gap junction that increases intercellular communication, similar to those found in normal breast tissue. BRMS1 is stabilized by Hsp90 and may inhibit NF-ⅹB activity.
Also known as:
AV003220;Anti-BRMS1抗体AW554636;Breast cancer metastasis suppressor 1 ; BRMS-1; BRMS1; BRMS 1; DKFZp564A063;MGC95128; BRMS1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from human BRMS-1 C-terminus.
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Predicted Molecular Weight: 28kDa.
Storage:
Shipped Anti-BRMS1抗体at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal Anti-BRMS1抗体working dilutions must be determined by the end user.
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