- 如果您对该产品感兴趣的话,可以
- 产品名称:Anti-phospho-BAD (Ser75)抗体
- 产品型号:磷酸化相关死亡促进因子抗体
- 产品展商:KALANG
- 产品文档:无相关文档
- 发布时间:2016-05-13
- 在线询价
简单介绍
Anti-phospho-BAD (Ser75)抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-BAD (Ser75)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-phospho-BAD (Ser75)
Cat. Number:
Anti-phospho-BAD (Ser75)抗体KL-3009R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrialAnti-phospho-BAD (Ser75)抗体 membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of Anti-phospho-BAD (Ser75)抗体this gene results in two transcript variants which encode the same isoform.
Also known as:
Bad (phospho S75); Bad (phospho Ser75); p-Bad (S75);p- Bad (Ser75); p-Bad (phospho Ser75); BBC 2; BBC2; BBC6; Anti-phospho-BAD (Ser75)抗体Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein; BAD_HUMAN; Bcl-2-binding component 6.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Horse, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human BAD around the phosphorylation site of Ser75.
●
Predicted Molecular Weight: 22kDa.
Storage:
Shipped at 4℃, Store Anti-phospho-BAD (Ser75)抗体at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl015Ra01 骨成型蛋白受体1A(BMPR1A)多克隆抗体 Polyclonal Antibody to Bone Morphogenetic Protein Receptor 1A (BMPR1A)
kl017Bo01 上皮性钙黏附蛋白(CDHE)多克隆抗体 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Ga01 上皮性钙黏附蛋白(CDHE)多克隆抗体 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Hu01 上皮性钙黏附蛋白(CDHE)多克隆抗体 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Mu01 上皮性钙黏附蛋白(CDHE)多克隆抗体 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Po01 上皮性钙黏附蛋白(CDHE)多克隆抗体 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl017Ra01 上皮性钙黏附蛋白(CDHE)多克隆抗体 Polyclonal Antibody to Cadherin, Epithelial (CDHE)
kl019Hu01 白介素8受体α(IL8Rα)多克隆抗体 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl019Mu01 白介素8受体α(IL8Rα)多克隆抗体 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl019Ra01 白介素8受体α(IL8Rα)多克隆抗体 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl019Rb51 白介素8受体α(IL8Rα)多克隆抗体 Polyclonal Antibody to Interleukin 8 Receptor Alpha (IL8Ra)
kl021Ga01 睫状神经营养因子(CNTF)多克隆抗体 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Hu01 睫状神经营养因子(CNTF)多克隆抗体 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Mu01 睫状神经营养因子(CNTF)多克隆抗体 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Po01 睫状神经营养因子(CNTF)多克隆抗体 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Ra01 睫状神经营养因子(CNTF)多克隆抗体 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl021Rb51 睫状神经营养因子(CNTF)多克隆抗体 Polyclonal Antibody to Ciliary Neurotrophic Factor (CNTF)
kl022Bo01 血管内皮细胞蛋白C受体(PROCR)多克隆抗体 Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Ga01 血管内皮细胞蛋白C受体(PROCR)多克隆抗体 Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)
kl022Hu01 血管内皮细胞蛋白C受体(PROCR)多克隆抗体 Polyclonal Antibody to Protein C Receptor, Endothelial (PROCR)