- 如果您对该产品感兴趣的话,可以
- 产品名称:Anti-Phospho-Bad (Ser112)抗体
- 产品型号:磷酸化相关死亡促进因子抗体
- 产品展商:KALANG
- 产品文档:无相关文档
- 发布时间:2016-05-13
- 在线询价
简单介绍
Anti-Phospho-Bad (Ser112)抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-Bad (Ser112)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-Phospho-Bad (Ser112)
Cat. Number:
Anti-Phospho-Bad (Ser112)抗体KL-3040R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory Anti-Phospho-Bad (Ser112)抗体effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Also known as:
Bad (phospho S112); Bad (phospho Ser112); p-Bad (S112);p- Bad (Ser112); p-Bad (phospho Ser112); BBC 2; BBC2; BBC6; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; Anti-Phospho-Bad (Ser112)抗体BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein; BAD_HUMAN; Bcl-2-binding component 6.
Specificity:
●
Rabbit Polyclonal IgG, Anti-Phospho-Bad (Ser112)抗体affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Horse, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from mouse BAD around the phosphorylation site of Ser112.
●
Predicted Molecular Weight: 22kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 Anti-Phospho-Bad (Ser112)抗体ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl085Ca01 白血病抑制因子(LIF)多克隆抗体 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF)
kl085Cp01 白血病抑制因子(LIF)多克隆抗体 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF)
kl085Hu01 白血病抑制因子(LIF)多克隆抗体 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF)
kl085Mu01 白血病抑制因子(LIF)多克隆抗体 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF)
kl085Po01 白血病抑制因子(LIF)多克隆抗体 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF)
kl085Ra01 白血病抑制因子(LIF)多克隆抗体 Polyclonal Antibody to Leukemia Inhibitory Factor (LIF)
kl086Bo01 L选择素(SELL)多克隆抗体 Polyclonal Antibody to Selectin, Leukocyte (SELL)
kl086Hu01 L选择素(SELL)多克隆抗体 Polyclonal Antibody to Selectin, Leukocyte (SELL)
kl086Mu01 L选择素(SELL)多克隆抗体 Polyclonal Antibody to Selectin, Leukocyte (SELL)
kl086Ra01 L选择素(SELL)多克隆抗体 Polyclonal Antibody to Selectin, Leukocyte (SELL)
kl087Ca01 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl087Hu01 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl087Mu01 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl087Po01 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl087Ra01 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl087Rb53 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl087Si01 单核细胞趋化蛋白1(MCP1)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
kl088Bo01 单核细胞趋化蛋白2(MCP2)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 2 (MCP2)
kl088Ca01 单核细胞趋化蛋白2(MCP2)多克隆抗体 Polyclonal Antibody to Monocyte Chemotactic Protein 2 (MCP2)