Anti-phospho-Bcl-xL (Thr115)抗体

Cat. Number:

Anti-phospho-Bcl-xL (Thr115)抗体KL-5234R

Quantity size:

0.1ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Anti-phospho-Bcl-xL (Thr115)抗体The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorterAnti-phospho-Bcl-xL (Thr115)抗体 form acts as an apoptotic activator. [provided by RefSeq, Jul 2008].

Also known as:

BCL2L1 (phospho T115); BCL2L1 (phospho Thr115); p-Bcl-xL(Thr115); p-BCL2L1(Thr115); Apoptosis regulator Bcl X; BclX; Bcl-X; Bcl 2 like 1; Bcl 2 like 1 protein; Bcl xL; BCL X/L; BCL XL/S; Bcl xS; Bcl2 like1; BCL2-related gene; BCL2-related protein, long isoform, included; BCLXL, included; BCL2-related protein, short isoform, included; BCLXS, included; BCL2L; BCL2L1; Bclx; DKFZp781P2092; MGC113803; Anti-phospho-Bcl-xL (Thr115)抗体MGC99998; B2CL1_HUMAN.

Specificity:

Storage:

Shipped at 4℃, Anti-phospho-Bcl-xL (Thr115)抗体Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.