Anti-BCAS2抗体

Cat. Number:

Anti-BCAS2抗体KL-6610R

Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

BCAS2 is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in variousAnti-BCAS2抗体 breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with thyroid hormone receptor beta, ER alpha (estrogen receptor alpha), PR (progesterone receptor), and PPAR gamma (Peroxisome proliferator-activated receptor gamma). BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated Anti-BCAS2抗体transcription. This suggests that BCAS2 is involved in the development of breast cancer.

Also known as:

DNA amplified in mammary carcinoma 1 protein; Spliceosome associated protein SPF 27; bcas2; Breast carcinoma amplifiedAnti-BCAS2抗体 sequence 2; Breast carcinoma-amplified sequence 2; DAM1; MGC7712; Pre mRNA splicing factor SPF27; Pre-mRNA-splicing factor spf27; SPF27_HUMAN; Spliceosome associated protein amplified in breast cancer; Spliceosome-associated protein SPF 27.

Specificity:

Storage:

Shipped at 4℃, StoreAnti-BCAS2抗体 at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.