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- 产品名称:Anti-phospho-PML Protein (Ser518)抗体
- 产品型号:磷酸化早幼粒细胞白血病蛋白抗体
- 产品展商:KALANG
- 产品文档:无相关文档
- 发布时间:2018-09-11
- 在线询价
简单介绍
Anti-phospho-PML Protein (Ser518)抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-PML Protein (Ser518)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-phospho-PML Protein (Ser518)
Cat. Number:
Anti-phospho-PML Protein (Ser518)抗体KL-12793R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression isAnti-phospho-PML Protein (Ser518)抗体 cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Also known as:
PML Protein (phospho S518); p-PML Anti-phospho-PML Protein (Ser518)抗体Protein (phospho S518); Acure promyelocytic leukemia, inducer of; MYL; Pml; PML_HUMAN; PP8675; Probable transcription factor PML; Promyelocytic leukemia; Promyelocytic leukemia inducer of; Promyelocytic leukemia protein; Protein PML; RING finger protein 71; RNF 71; TRIM 19; Tripartite motif protein TRIM19; Tripartite motif-containing protein 19.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, .
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Immunogen: KLH conjugated synthesised Anti-phospho-PML Protein (Ser518)抗体phosphopeptide derived from human PML Protein around the phosphorylation site of Ser518.
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Predicted Molecular Weight: 110kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-PML Protein (Ser518)抗体
Optimal working dilutions must be determined by the end user.