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- 产品名称：Anti-RAD51C/TDRD1抗体
- 产品型号：乳腺癌和卵巢癌易感基因RAD51C抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-06-17
- 在线询价
简单介绍
Anti-RAD51C/TDRD1抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-RAD51C/TDRD1抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-RAD51C/TDRD1
Cat. Number:
Anti-RAD51C/TDRD1抗体KL-2186R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Essential for the homologous recombination (HR) pathway of DNA repair. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. Anti-RAD51C/TDRD1抗体The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Participates in branch migration and Holliday junction resolution and thus is important for processing HR intermediates late in the DNA repair process. Also has an early function in DNA repair in facilitating phosphorylation of the checkpoint kinase CHK2 and thereby transduction of the damage signal, leading to cell cycle arrest and HR activation. Protects RAD51 from ubiquitin-mediated degradation that is enhanced following DNA damage. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and XRCC3. Contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Involved in maintaining centrosome number in mitosis.
Also known as:
tudor domain containing 1; Tdrd1;Anti-RAD51C/TDRD1抗体 MTR-1; MTR 1; FLJ21082; CT41.1; TDRD1_HUMAN. Cancer/testis antigen 41.1; TDRD 1; tdrd1; Tudor domain containing protein 1; Tudor domain-containing protein 1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .
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Immunogen: KLH conjugated synthetic Anti-RAD51C/TDRD1抗体peptide derived from human TDRD1.
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Predicted Molecular Weight: 132kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-RAD51C/TDRD1抗体
Optimal working dilutions must be determined by the end user.
