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- 产品名称：Anti-Phospho-P105 RB (Ser788)抗体
- 产品型号：磷酸化视网膜母细胞瘤相关蛋白1抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-07-03
- 在线询价
简单介绍
Anti-Phospho-P105 RB (Ser788)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Phospho-P105 RB (Ser788)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-Phospho-P105 RB (Ser788)
Cat. Number:
Anti-Phospho-P105 RB (Ser788)抗体KL-5665R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including Anti-Phospho-P105 RB (Ser788)抗体E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Also known as:
RB1(phospho S788); Rb(Phospho-Ser788); Anti-Phospho-P105 RB (Ser788)抗体p105-Rb (phospho-Ser788); p105-Rb (phospho Ser788); p-Rb (Ser788); OSRC; P105 RB; P105RB; PP105; PP110; pRb; RB 1; RB1; RB1 protein; Retinoblastoma 1 (including osteosarcoma); Retinoblastoma 1; Retinoblastoma associated protein; Retinoblastoma related osteosarcoma; Retinoblastoma susceptibility gene; Including osteosarcoma; RB_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Anti-Phospho-P105 RB (Ser788)抗体Pig, Cow, Horse, Rabbit, Sheep, .
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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Ser788.
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Predicted Molecular Weight: 102kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phospho-P105 RB (Ser788)抗体
Optimal working dilutions must be determined by the end user.
