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- 产品名称：Anti-Repulsive Guidance Molecule B抗体
- 产品型号：反义导向分子RGMB抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-06-22
- 在线询价
简单介绍
Anti-Repulsive Guidance Molecule B抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-Repulsive Guidance Molecule B抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-Repulsive Guidance Molecule B
Cat. Number:
Anti-Repulsive Guidance Molecule B抗体KL-11474R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons. They are repulsive for a group of axons, those from the temporal half of the retina. RGM have beenAnti-Repulsive Guidance Molecule B抗体 implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, semaphorins, netrins and slits, no receptor mechanism for RGM activation has been defined. Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness. The RGM proteins are attached to the membrane by a GPI-anchor. Two members of this family, RGMa and RGMb, are expressed in the nervous system. RGMc, also known as Hemojuvelin, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut. Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH).
Also known as:
RGMB; Dragon; DRG11-responsive Anti-Repulsive Guidance Molecule B抗体axonal guidance and outgrowth of neurite; Repulsive Guidance Molecule B; RGM b; RGM domain family member B; Rgmb; RGMB_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .
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Immunogen: KLH conjugated synthetic Anti-Repulsive Guidance Molecule B抗体peptide derived from human Repulsive Guidance Molecule B.
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Predicted Molecular Weight: 40kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Anti-Repulsive Guidance Molecule B抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
