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- 产品名称：Anti-REA抗体
- 产品型号：B**细胞受体相关蛋白抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-08-05
- 在线询价
简单介绍
Anti-REA抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-REA抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-REA
Cat. Number:
Anti-REA抗体KL-10283R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The prohibitins, called PHB1 and PHB2, are highly conserved proteins that are present in nuclear and mitochondrial compartments in eukaryotic cells and exert multiple cellular functions (1). PHB2 (REA) was originally identified asAnti-REA抗体 an estrogen receptor (ER) specific coregulator. It directly interacts with hormone-bound ER and represses its transcriptional activity by competitive inhibition of SRC-1 coactivation of ER (2,3). Together with COUP-TFs, PHB2 also interacts with histone deacetylases HDAC1 and HDAC5, and mediates transcriptional regulation by ER through coupling the deacetylase to the transcription activation complex (4). Another important function of PHB2 is stablization of mitochondrial proteins. PHB1/PHB2 hetrodimers form large ring complexes on the mitochondrial membrane (5), acting as chaperones to stablize important mitochodrial proteins, such as OPA1 and Hax1 to support mitochondrial morphogenesis and protection against apoptosis (6-8).
Also known as:
B cell receptor associated protein BAP37; B-cell associated protein; B-cell receptor-associated protein BAP37; Bap 37; BAP; Bap37; Anti-REA抗体BCAP 37; BCAP37; D prohibitin; D-prohibitin; MGC117268; p22; PHB 2; PHB2; PHB2_HUMAN; PNAS 141; PNAS141; Prohibitin 2; Prohibitin-2; Prohibitin2; Repressor of Estrogen Receptor Activity.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated syntheticAnti-REA抗体 peptide derived from human REA.
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Predicted Molecular Weight: 33kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-REA抗体
Optimal working dilutions must be determined by the end user.
