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- 产品名称：Anti-SPRN抗体
- 产品型号：新朊蛋白抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-09-08
- 在线询价
简单介绍
Anti-SPRN抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-SPRN抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-SPRN
Cat. Number:
Anti-SPRN抗体KL-2149R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are manifested as genetic, infectious or sporadic lethal neurodegenerative disorders involving alterations of the prion protein (PrP). Constitutively expressed Anti-SPRN抗体in normal ***** brain, cellular PrP (PrP(C)) is sensitive to proteinase K digestion and is converted to the disease form, PrPSc, through alterations in protein folding conformation, which make it resistant proteases. SPRN (shadow of prion protein), also known as SHO or SHADOO, is a 151 amino acid cytoplasmic protein that is mainly expressed in brain. SPRN is considered a prion-like protein that has PrP(C)-like neuroprotective activity and may act as a modulator for the biological actions of normal and abnormal PrP. In humans, mutations in the gene encoding SPRN may be associated with variant and sporadic Creutzfeldt-Jakob disease, a degenerative neurological disorder that is incurable and invariably fatal
Also known as:
rCG47959; shadow of prion protein; Anti-SPRN抗体SHO; Protein shadoo; bA108K14.1; C630041J07; FLJ41197; SPRN; Shadow of prion protein precursor; SPRN_MOUSE; SHADOO.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Mouse, Rat, .
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Immunogen: KLH conjugated synthetic Anti-SPRN抗体peptide derived from mouse Shadow.
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Predicted Molecular Weight: 12kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-SPRN抗体
Optimal working dilutions must be determined by the end user.
