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- 产品名称:Anti-phospho-SHC (Tyr239 + Tyr240)抗体
- 产品型号:磷酸化SH2结构域转化蛋白1抗体
- 产品展商:KALANG
- 产品文档:无相关文档
- 发布时间:2018-07-10
- 在线询价
简单介绍
Anti-phospho-SHC (Tyr239 + Tyr240)抗体产品质量稳定,实验效果明显,货期快,价格优惠,欢迎垂询订购!我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-SHC (Tyr239 + Tyr240)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-phospho-SHC (Tyr239 + Tyr240)
Cat. Number:
Anti-phospho-SHC (Tyr239 + Tyr240)抗体KL-3414R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in Anti-phospho-SHC (Tyr239 + Tyr240)抗体signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Also known as:
SHC (phospho Tyr239 + Tyr240); SHC (phospho Y239 + Y240); p-SHC (Tyr239 + Tyr240); p-SHC (Y239 + Y240); p46; p52; p52 SHC; p52SHC; p66; p66 SHC; p66SHC; SH2 domain protein C1; SHC (Src homology 2 domain Anti-phospho-SHC (Tyr239 + Tyr240)抗体containing) transforming protein 1; SHC 1; SHC A; Shc; SHC transforming protein 1; SHC transforming protein; SHC1; SHCA; Src homology 2 domain containing transforming protein C1.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, .
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Immunogen: KLH conjugated Anti-phospho-SHC (Tyr239 + Tyr240)抗体Synthesised phosphopeptide derived from human SHC around the phosphorylation site of Tyr239/240.
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Predicted Molecular Weight: 41kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-SHC (Tyr239 + Tyr240)抗体
Optimal working dilutions must be determined by the end user.