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- 产品名称：Anti-SAMHD1/MOP5抗体
- 产品型号：单核细胞蛋白5抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-08-04
- 在线询价
简单介绍
Anti-SAMHD1/MOP5抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-SAMHD1/MOP5抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-SAMHD1/MOP5
Cat. Number:
Anti-SAMHD1/MOP5抗体KL-8060R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. Anti-SAMHD1/MOP5抗体May play a role in mediating proinflammatory responses to TNF-alpha signaling.
Tissue specificity: Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.
Involvement in disease:
Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) . A form of Aicardi-Goutieres syndrome, a genetically heterogeneous disease characterized by cerebral atrophy, leukoencephalopathy, intracranial calcifications, chronic cerebrospinal fluid (CSF) lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infection. Clinical features as thrombocytopenia, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process. Severe neurological dysfunctions manifest in infancy as progressive microcephaly, spasticity, dystonic posturing and profound psychomotor retardation. Death often occurs in early childhood.
Also known as:
DCIP; Dendritic cell derived IFNG induced protein; Anti-SAMHD1/MOP5抗体Dendritic cell-derived IFNG-induced protein; HD domain containing 1; HDDC1; Mg11; Monocyte protein 5; MOP 5; MOP5; OTTHUMP; SAM domain and HD domain 1; SAM domain and HD domain containing protein 1; SAM domain and HD domain-containing protein 1; SAMH1_HUMAN; Samhd1; SBBI88.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Cow, Horse, Zebrafish, Sheep, .
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Immunogen: KLH conjugated synthetic peptideAnti-SAMHD1/MOP5抗体 derived from human SAMHD1/HDDC1/MOP5.
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Predicted Molecular Weight: 72kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-SAMHD1/MOP5抗体
Optimal working dilutions must be determined by the end user.
