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- 产品名称：Anti-phospho-c-Abl (Ser569)抗体
- 产品型号：磷酸化非受体酪氨酸激酶c-Abl抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-07-28
- 在线询价
简单介绍
Anti-phospho-c-Abl (Ser569)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-c-Abl (Ser569)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-phospho-c-Abl (Ser569)
Cat. Number:
Anti-phospho-c-Abl (Ser569)抗体KL-12904R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. Anti-phospho-c-Abl (Ser569)抗体The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
Also known as:
c Abl(phospho S569); p-c Abl(phospho S569);Anti-phospho-c-Abl (Ser569)抗体 p-c Abl(phospho Ser569); Abelson Murine Leukemia Viral Oncogene Homolog 1; Abelson murine leukemia viral v abl oncogene homolog 1; Abl 1; ABL; Abl protein; Abl1; Bcr/c abl oncogene protein; JTK 7; JTK7; p150 ; Proto oncogene tyrosine protein kinase ABL1; Transformation gene oncogene ABL; v abl Abelson murine leukemia viral oncogene homolog 1; v abl; ABL1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated Anti-phospho-c-Abl (Ser569)抗体synthesised phosphopeptide derived from human c-Abl isoform a around the phosphorylation site of Ser569.
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Predicted Molecular Weight: 123kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Anti-phospho-c-Abl (Ser569)抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
