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- 产品名称：Anti-phospho-SLP76 (Tyr145)抗体
- 产品型号：磷酸化**细胞胞浆蛋白2抗体
- 产品展商：KALANG
- 产品文档：无相关文档
- 发布时间：2018-08-25
- 在线询价
简单介绍
Anti-phospho-SLP76 (Tyr145)抗体产品质量稳定，实验效果明显，货期快，价格优惠，欢迎垂询订购！我公司长期供应**组化抗体、WB抗体、**组化试剂盒和抗体试验所需全部相关试剂、荧光标记抗体、单克隆抗体、多克隆抗体、各种标记的二抗IgG/IgM/IgD/IgA等科研实验抗体。Anti-phospho-SLP76 (Tyr145)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
产品描述
Rabbit Anti-phospho-SLP76 (Tyr145)
Cat. Number:
Anti-phospho-SLP76 (Tyr145)抗体KL-13662R
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The translational product of the Vav proto-oncogene is exclusively expressed in cells of hematopoietic origin and is critical for lymphocyte development and activation. However, the biochemical basis of Vav’s function is unclear. Vav contains a single SH2 domain that is required for its association with the T cell receptor (TCR). Overexpression of Vav or SLP-76 in Jurkat cells leads to NFAT activation and IL-2 production. When co-expressed, Vav and SLP-76 synergize to induce a robust basal and TCR-mediated IL-2Anti-phospho-SLP76 (Tyr145)抗体response. Although SLP-76 does not contain a motif that would indicate it to be a member of the tyrosine, serine/threonine or lipid kinase families, it does contain several putative SH2/SH3-binding domains and has been shown to physically associate with the adapter protein GRB2 as well as PLC g1. The discovery of SLP-76 represents an important step in elucidating the mechanism of Vav transformation and TCR-mediated NFAT activation.
Also known as:
SLP76 (phospho Y145); p-SLP76 (Y145); Anti-phospho-SLP76 (Tyr145)抗体p-LCP2; 76 kDa tyrosine phosphoprotein; CG8697; LCP 2; LCP 2; LCP2; LCP2_HUMAN; Lymphocyte Cytosolic Protein 2; Lymphocyte Cytosolic Protein 2; SH2 Domain Containing Leukocyte Protein 76 KD; SH2 domain containing leukocyte protein of 76kD; SH2 domain containing leukocyte protein of 76kDa; SH2 domain-containing leukocyte protein of 76 kDa; SLP 76; SLP 76; SLP 76 tyrosine phosphoprotein; SLP-76 tyrosine phosphoprotein; SLP76; SLP76 tyrosine phosphoprotein.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated Synthesised Anti-phospho-SLP76 (Tyr145)抗体phosphopeptide derived from human SLP76 around the phosphorylation site of Tyr145.
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Predicted Molecular Weight: 60kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-SLP76 (Tyr145)抗体
Optimal working dilutions must be determined by the end user.
