CD3 Peptides
Product Name: CD3 Peptides
Cat. Number: hz-0765P
Quantity size: 500ug
Source: Synthetic Peptide
Form: lyophilized powde
Purity: ≥95% (Purified by HPLC)
Storage: Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application: Immunology research
Blocking Peptide of The hz-0765R Antibody
Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Also known as: CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景：该基因编码的蛋白质的CD3ε多肽，连同CD3γ-δ和Zeta和T细胞受体α/β和γδT细胞受体CD3复合物形成的异源二聚体。这种复合物在抗原识别与细胞内信号转导通路的偶联中起着重要作用。编码ε、γ和δ多肽的基因位于11号染色体上的同一簇中。ε-多肽在T细胞发育中起着重要作用。这个基因的缺陷导致**缺陷。该基因也与女性I型糖尿病易感性有关。[由RefSeq提供，月2008日]。
又名：CD3εεεε多肽抗原；；（tit3复杂）；εε多肽抗原；抗原CD3ε，ε亚基；CD3εεεε分子；分子（CD3 TCR复合物分子）；ε，ε（CD3-TCR复合物）；cd3e_human；imd18；T细胞抗原受体复合物ε亚基T3；T细胞表面抗原T3 /亮氨酸4ε链；T细胞表面的糖蛋白CD3ε链；T细胞表面抗原T3 /亮氨酸-4链；T细胞表面糖蛋白CD3ε链；T3E；TCRE。
