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- 产品名称： IGF 1R (phospho Tyr1165 / Tyr1166) Antibody
- 产品型号：
- 产品展商：immunoclone
- 产品文档：无相关文档
- 发布时间：2018-06-22
- 在线询价
简单介绍
IGF 1R (phospho Tyr1165 / Tyr1166) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。 IGF 1R (phospho Tyr1165 / Tyr1166) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。
产品描述
IGF 1R (phospho Tyr1165 / Tyr1166) AntibodyProduct Profile
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Product Name
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IGF 1R (phospho Tyr1165 / Tyr1166) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.1) Li S, et al. (1994) J Biol Chem; 269 (51): 32558-64.
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Immunogen
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IGF-1R (Phospho-Tyr1165/Tyr1166) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y (p) -Y (p) -R-K) derived from Human IGF-1R .
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IGF 1R (phospho Tyr1165 / Tyr1166) AntibodyKey Feature
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Clonality
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Polyclonal
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Host Species
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Rabbit
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Tested Applications
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IFWB
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Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
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Species Reactivity
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HumanMouseRat
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Concentration
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1mg/ml
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Purification
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Affinity purified
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IGF 1R (phospho Tyr1165 / Tyr1166) AntibodyTarget Information
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Gene Symbol
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IGF1R
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Alternative Names
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IGFR
CD221
IGFIR
JTK13
RAB5
Insulin-like growth factor I receptor
IGF1R
kinase IGF1R
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Molecular Weight(MW)
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200, 95 kDa
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Tissue Specificity
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This antibody detects endogenous level of IGF-1R onlywhen phosphorylated at tyrosine 1165/tyrosine1166.
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IGF 1R (phospho Tyr1165 / Tyr1166) AntibodyDatabase Links
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Entrez Gene
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3480
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Protein Accession
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NP_000866.1
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IGF 1R (phospho Tyr1165 / Tyr1166) AntibodyApplication
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Application
Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R (Phospho-Tyr1165/Tyr1166).
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Application
Western blot analysis of lysed extracts from 293 cells untreated or treated with insulin using IGF-1R (Phospho-Tyr1165/Tyr1166).
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Application Notes
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Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200:
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Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20˚C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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