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- 产品名称：FGFR1/2 (phospho Tyr463/466) Antibody
- 产品型号：
- 产品展商：immunoclone
- 产品文档：无相关文档
- 发布时间：2017-08-16
- 在线询价
简单介绍
FGFR1/2 (phospho Tyr463/466) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。FGFR1/2 (phospho Tyr463/466) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。
产品描述
FGFR1/2 (phospho Tyr463/466) AntibodyProduct Profile
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Product Name
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FGFR1/2 (phospho Tyr463/466) Antibody
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Antibody Type
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Primary Antibodies
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Product description
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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.1) Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990).
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Immunogen
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FGFR1/2 (phospho Tyr463/466) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 463/466 (S-E-Y (p)-E-L) derived from Human FGFR1/2.
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FGFR1/2 (phospho Tyr463/466) AntibodyKey Feature
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Clonality
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Polyclonal
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Isotype
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IgG
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Host Species
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Rabbit
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Tested Applications
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WB
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Species Reactivity
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HumanMouse
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Concentration
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1mg/ml
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Purification
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Affinity purified
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FGFR1/2 (phospho Tyr463/466) AntibodyTarget Information
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Gene Symbol
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FGFR1, FGFR2
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Alternative Names
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BFGFR
CEK
FLG
CD331
FLT2
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Molecular Weight(MW)
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91 kDa
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Tissue Specificity
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The antibody detects endogenous levels of FGFR1/2 only when phosphorylated at tyrosine 463/466.
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FGFR1/2 (phospho Tyr463/466) AntibodyDatabase Links
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Entrez Gene
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2260/2263
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Protein Accession
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NP_075598.2
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FGFR1/2 (phospho Tyr463/466) AntibodyApplication
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Application
Western blot analysis of extracts from HepG2 cells using FGFR1/2 (Phospho-Tyr463/466) Antibody. The lane on the right is treated with the antigen-specific peptide.
Additional Information
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Form
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Liquid
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Storage Instructions
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Store antibody at -20˚C for up to one year.
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Storage Buffer
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Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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