产品名称：Anti-Ataxin 1抗体

Cat. Number:

YB2732R

Quantity size:

0.1ml

Concentration:

Anti-Ataxin 1抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Anti-Ataxin 1抗体The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Also known as:

Anti-Ataxin 1抗体ATX1; ATXN1; SCA1; Ataxin 1; Ataxin-1; Ataxin1; Spinocerebellar ataxia type 1; ATX1_HUMAN.

Specificity:

Storage:

Anti-Ataxin 1抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-Ataxin 1抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.yb643Mu01 白介素13受体α2(IL13Rα2)多克隆抗体 Polyclonal Antibody to Interleukin 13 Receptor Alpha 2 (IL13Ra2) Mus musculus (Mouse)
yb646Hu01 黑素瘤衍生亮氨酸拉链额外核因子(MLZE)多克隆抗体 Polyclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Homo sapiens (Human)
yb647Hu01 趋化因子C-C-基元受体7(CCR7)多克隆抗体 Polyclonal Antibody to Chemokine C-C-Motif Receptor 7 (CCR7) Homo sapiens (Human)
yb647Mu01 趋化因子C-C-基元受体7(CCR7)多克隆抗体 Polyclonal Antibody to Chemokine C-C-Motif Receptor 7 (CCR7) Mus musculus (Mouse)
yb649Hu01 钾氯协同转运蛋白2(KCC2)多克隆抗体 Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) Homo sapiens (Human)
yb651Hu01 皮肤T-细胞虏获趋化因子(CTACK)多克隆抗体 Polyclonal Antibody to Cutaneous T-Cell Attracting Chemokine (CTACK) Homo sapiens (Human)
yb652Hu01 白介素18受体1(IL18R1)多克隆抗体 Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) Homo sapiens (Human)
yb653Ga01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Chicken (Gallus)
yb653Hu01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Homo sapiens (Human)
yb653Mu01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Mus musculus (Mouse)
yb653Ra01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Rattus norvegicus (Rat)
yb655Hu01 白介素18受体辅助蛋白(IL18RAP)多克隆抗体 Polyclonal Antibody to Interleukin 18 Receptor Accessory Protein (IL18RAP) Homo sapiens (Human)
yb657Ra01 肉毒碱脂酰转移酶(CACT)多克隆抗体 Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) Rattus norvegicus (Rat)