企业信息
第7年
- 入驻时间： 2015-11-06
- 联系人：顾磊
- 电话：021-60514606
-
联系时，请说明易展网看到的
- Email：shybio@126.com
产品分类
产品详情
简单介绍：
Anti-ATK/BTK抗体供应商为您提供抗体的售前、售中、售后服务，现货供应，保证实验结果，无效可以免费退换，广泛应用于IHC、WB、 IF、IP、ELISA，质量保证，另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂，Anti-ATK/BTK抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-ATK/BTK
Cat. Number:
YB2752R
Quantity size:
0.2ml
Concentration:
Anti-ATK/BTK抗体1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Anti-ATK/BTK抗体Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.
Also known as:
Anti-ATK/BTK抗体Agammaglobulinaemia tyrosine kinase; AGMX 1; AGMX1; AT; ATK; B cell progenitor kinase; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton’s Tyrosine Kinase; Btk; BTK_HUMAN; IMD 1; IMD1; MGC126261; MGC126262; OTTHUMP00000063593; PSCTK 1; PSCTK1; Tyrosine protein kinase BTK; Tyrosine-protein kinase BTK; XLA.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human BTK.
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Predicted Molecular Weight: 76kDa.
Storage:
Anti-ATK/BTK抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-ATK/BTK抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.yb034Hu01 生长分化因子15(GDF15)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Homo sapiens (Human)
yb034Mu01 生长分化因子15(GDF15)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Mus musculus (Mouse)
yb034Ra01 生长分化因子15(GDF15)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Rattus norvegicus (Rat)
yb035Hu01 S100钙结合蛋白A7(S100A7)多克隆抗体 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) Homo sapiens (Human)
yb035Mu01 S100钙结合蛋白A7(S100A7)多克隆抗体 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) Mus musculus (Mouse)
yb040Hu01 葡萄糖转运蛋白2(GLUT2)多克隆抗体 Polyclonal Antibody to Glucose Transporter 2 (GLUT2) Homo sapiens (Human)
yb041Hu01 过氧化物酶体增殖物激活受体δ(Pklδ)多克隆抗体 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Delta (Pkld) Homo sapiens (Human)
yb042Hu01 法尼酯X受体(FXR)多克隆抗体 Polyclonal Antibody to Farnesoid X Receptor (FXR) Homo sapiens (Human)
yb042Mu01 法尼酯X受体(FXR)多克隆抗体 Polyclonal Antibody to Farnesoid X Receptor (FXR) Mus musculus (Mouse)
yb044Hu01 肝X受体α(LXRα)多克隆抗体 Polyclonal Antibody to Liver X Receptor Alpha (LXRa) Homo sapiens (Human)
yb045Hu01 存活素(Surv)多克隆抗体 Polyclonal Antibody to Survivin (Surv) Homo sapiens (Human)
yb045Mu01 存活素(Surv)多克隆抗体 Polyclonal Antibody to Survivin (Surv) Mus musculus (Mouse)
yb047Hu01 Ki-67蛋白(Ki67P)多克隆抗体 Polyclonal Antibody to Ki-67 Protein (Ki67P) Homo sapiens (Human)
yb047Mu01 Ki-67蛋白(Ki67P)多克隆抗体 Polyclonal Antibody to Ki-67 Protein (Ki67P) Mus musculus (Mouse)
yb047Ra01 Ki-67蛋白(Ki67P)多克隆抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.yb034Hu01 生长分化因子15(GDF15)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Homo sapiens (Human)
yb034Mu01 生长分化因子15(GDF15)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Mus musculus (Mouse)
yb034Ra01 生长分化因子15(GDF15)多克隆抗体 Polyclonal Antibody to Growth Differentiation Factor 15 (GDF15) Rattus norvegicus (Rat)
yb035Hu01 S100钙结合蛋白A7(S100A7)多克隆抗体 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) Homo sapiens (Human)
yb035Mu01 S100钙结合蛋白A7(S100A7)多克隆抗体 Polyclonal Antibody to S100 Calcium Binding Protein A7 (S100A7) Mus musculus (Mouse)
yb040Hu01 葡萄糖转运蛋白2(GLUT2)多克隆抗体 Polyclonal Antibody to Glucose Transporter 2 (GLUT2) Homo sapiens (Human)
yb041Hu01 过氧化物酶体增殖物激活受体δ(Pklδ)多克隆抗体 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Delta (Pkld) Homo sapiens (Human)
yb042Hu01 法尼酯X受体(FXR)多克隆抗体 Polyclonal Antibody to Farnesoid X Receptor (FXR) Homo sapiens (Human)
yb042Mu01 法尼酯X受体(FXR)多克隆抗体 Polyclonal Antibody to Farnesoid X Receptor (FXR) Mus musculus (Mouse)
yb044Hu01 肝X受体α(LXRα)多克隆抗体 Polyclonal Antibody to Liver X Receptor Alpha (LXRa) Homo sapiens (Human)
yb045Hu01 存活素(Surv)多克隆抗体 Polyclonal Antibody to Survivin (Surv) Homo sapiens (Human)
yb045Mu01 存活素(Surv)多克隆抗体 Polyclonal Antibody to Survivin (Surv) Mus musculus (Mouse)
yb047Hu01 Ki-67蛋白(Ki67P)多克隆抗体 Polyclonal Antibody to Ki-67 Protein (Ki67P) Homo sapiens (Human)
yb047Mu01 Ki-67蛋白(Ki67P)多克隆抗体 Polyclonal Antibody to Ki-67 Protein (Ki67P) Mus musculus (Mouse)
yb047Ra01 Ki-67蛋白(Ki67P)多克隆抗体
