产品详情
  • 产品名称:Anti-ARRDC3抗体

  • 产品型号:抑制蛋白结构域蛋白3抗体
  • 产品厂商:科研抗体
  • 产品价格:0
  • 折扣价格:0
  • 产品文档:
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简单介绍:
Anti-ARRDC3抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-ARRDC3抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍:
Rabbit  Anti-ARRDC3
Cat. Number:
YB8077R
Quantity size:
0.1ml
Concentration:
Anti-ARRDC3抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptorAnti-ARRDC3抗体it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.
Also known as:
Anti-ARRDC3抗体ARRDC 3; Arrestin domain containing protein 3; KIAA1376; Thioredoxin binding protein 2 like inducible membrane; TLIMP; ARRD3_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse,Anti-ARRDC3抗体 Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .
Immunogen: KLH conjugated synthetic peptide derived from human ARRDC3 corresponding to amino acids 178-215..
Predicted Molecular Weight: 46kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-ARRDC3抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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