产品名称：Anti-AT2R2抗体

Cat. Number:

YB2133R

Quantity size:

0.1ml

Concentration:

Anti-AT2R2抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Anti-AT2R2抗体Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites.

Also known as:

Anti-AT2R2抗体AGTR 2; AGTR2; AGTR-2; AGTR2_HUMAN; angiotensin II receptor type 2; Angiotensin II Type 2; Angiotensin II type-2 receptor; Angiotensin receptor 2; AT 2; AT2; AT2R2 ATGR 2; ATGR2; ATGR-2; MRX 88; MRX88; Type 2 angiotensin II receptor; Type-2 angiotensin II receptor.

Specificity:

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-AT2R2抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.yb640Hu01 前列腺素D合酶(PTGDS)多克隆抗体 Polyclonal Antibody to Prostaglandin D2 Synthase, Hematopoietic (PTGDS) Homo sapiens (Human)
yb643Mu01 白介素13受体α2(IL13Rα2)多克隆抗体 Polyclonal Antibody to Interleukin 13 Receptor Alpha 2 (IL13Ra2) Mus musculus (Mouse)
yb646Hu01 黑素瘤衍生亮氨酸拉链额外核因子(MLZE)多克隆抗体 Polyclonal Antibody to Melanoma Derived Leucine Zipper Extra Nuclear Factor (MLZE) Homo sapiens (Human)
yb647Hu01 趋化因子C-C-基元受体7(CCR7)多克隆抗体 Polyclonal Antibody to Chemokine C-C-Motif Receptor 7 (CCR7) Homo sapiens (Human)
yb647Mu01 趋化因子C-C-基元受体7(CCR7)多克隆抗体 Polyclonal Antibody to Chemokine C-C-Motif Receptor 7 (CCR7) Mus musculus (Mouse)
yb649Hu01 钾氯协同转运蛋白2(KCC2)多克隆抗体 Polyclonal Antibody to Potassium Chloride Cotransporters 2 (KCC2) Homo sapiens (Human)
yb651Hu01 皮肤T-细胞虏获趋化因子(CTACK)多克隆抗体 Polyclonal Antibody to Cutaneous T-Cell Attracting Chemokine (CTACK) Homo sapiens (Human)
yb652Hu01 白介素18受体1(IL18R1)多克隆抗体 Polyclonal Antibody to Interleukin 18 Receptor 1 (IL18R1) Homo sapiens (Human)
yb653Ga01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Chicken (Gallus)
yb653Hu01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Homo sapiens (Human)
yb653Mu01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Mus musculus (Mouse)
yb653Ra01 肌肉生长抑制素(MSTN)多克隆抗体 Polyclonal Antibody to Myostatin (MSTN) Rattus norvegicus (Rat)
yb655Hu01 白介素18受体辅助蛋白(IL18RAP)多克隆抗体 Polyclonal Antibody to Interleukin 18 Receptor Accessory Protein (IL18RAP) Homo sapiens (Human)
yb657Ra01 肉毒碱脂酰转移酶(CACT)多克隆抗体 Polyclonal Antibody to Carnitine Acylcarnitine Translocase (CACT) Rattus norvegicus (Rat)
yb658Hu01 血管紧张素Ⅱ受体1(AGTR1)多克隆抗体 Polyclonal Antibody to Angiotensin II Receptor 1 (AGTR1) Homo sapiens (Human)
yb658Ra01 血管紧张素Ⅱ受体1(AGTR1)多克隆抗体