Anti-phospho-AKT1 (Tyr474)抗体磷酸化蛋白激酶AKT1抗体上海钰博生物科技有限公司

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产品名称：Anti-phospho-AKT1 (Tyr474)抗体
产品型号：磷酸化蛋白激酶AKT1抗体
产品厂商：科研抗体
产品价格：0
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简单介绍：

Anti-phospho-AKT1 (Tyr474)抗体供应商为您提供抗体的售前、售中、售后服务，现货供应，保证实验结果，无效可以免费退换，广泛应用于IHC、WB、 IF、IP、ELISA，质量保证，另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂，Anti-phospho-AKT1 (Tyr474)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。

详情介绍：

Rabbit Anti-phospho-AKT1 (Tyr474)

Cat. Number:

YB10133R

Quantity size:

0.1ml

Concentration:

Anti-phospho-AKT1 (Tyr474)抗体1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, Anti-phospho-AKT1 (Tyr474)抗体a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.

Also known as:

Anti-phospho-AKT1 (Tyr474)抗体AKT1 (phospho Y474); AKT1(phospho-Tyr474); AKT3 (phospho Y473); p-AKT3 (phospho Y473); phospho-AKT1(Tyr474); phospho-AKT2 (Tyr475); AKT1(phospho Tyr474); AKT2 (phospho Tyr475); AKT3(phospho Tyr473); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.

Specificity:

●

Rabbit Polyclonal IgG, affinity purified by Protein A.

●

Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, .

●

Immunogen: KLH conjugated synthesised phosphopeptide derived from human AKT1 around the phosphorylation site of Tyr474.

●

Predicted Molecular Weight: 56kDa.

Storage:

Shipped at 4℃, Anti-phospho-AKT1 (Tyr474)抗体Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

Anti-phospho-AKT1 (Tyr474)抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
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产品名称：Anti-phospho-AKT1 (Tyr474)抗体