企业信息
第7年
- 入驻时间： 2015-11-06
- 联系人：顾磊
- 电话：021-60514606
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联系时，请说明易展网看到的
- Email：shybio@126.com
产品分类
产品详情
简单介绍：
Anti-EME2抗体供应商为您提供抗体的售前、售中、售后服务，现货供应，保证实验结果，无效可以免费退换，广泛应用于IHC、WB、 IF、IP、ELISA，质量保证，另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂，Anti-EME2抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
详情介绍：
Rabbit Anti-EME2
Cat. Number:
YB14578R
Quantity size:
0.1ml
Concentration:
Anti-EME2抗体1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair Anti-EME2抗体(Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]
Eme2 is a 379 amino acids nuclear protein. As a member of the Eme2/Mms4 family, Eme2 associates with MUS81 to constitute a DNA structure-specific endonuclease. The MUS81-Eme2 complex cleaves branched DNA structures, especially those arising during stalled DNA replication such as replication forks and 3'Anti-EME2抗体 DNA flaps. Expressed as two alternatively spliced isoforms, Eme2 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. Defects in the gene encoding WDR59 may be associated with the rare disorder Rubinstein-Taybi syndrome or Crohn's disease, which is a gastrointestinal inflammatory condition.
Eme2 is a 379 amino acids nuclear protein. As a member of the Eme2/Mms4 family, Eme2 associates with MUS81 to constitute a DNA structure-specific endonuclease. The MUS81-Eme2 complex cleaves branched DNA structures, especially those arising during stalled DNA replication such as replication forks and 3'Anti-EME2抗体 DNA flaps. Expressed as two alternatively spliced isoforms, Eme2 is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. Defects in the gene encoding WDR59 may be associated with the rare disorder Rubinstein-Taybi syndrome or Crohn's disease, which is a gastrointestinal inflammatory condition.
Also known as:
EME1, S. pombe, homolog of, 2; Eme2; EME2_HUMAN; essential meiotic endonuclease 1 homolog 2; essential meiotic endonuclease 1, S.pombe, homolog of, 2; essential meiotic structure-specific endonuclease subunit 2; Anti-EME2抗体gs125; homolog of yeast EME1 endonuclease 2; Probable crossover junction endonuclease EME2; SLX2 structure-specific endonuclease subunit homolog B; SLX2B.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Pig, Cow, .
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Immunogen: KLH conjugated synthetic peptide derived from human EME2.
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Predicted Molecular Weight: 41kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Anti-EME2抗体
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
