产品名称：Anti-APPBP2/FITC抗体

Anti-APPBP2/FITC抗体

产品编号YB-11639R-FITC

英文名称Anti-APPBP2/FITC

中文名称FITC标记的β淀粉样蛋白前体蛋白结合蛋白2抗体

别    名amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1.

Anti-APPBP2/FITC抗体   

说 明 书100ul  

研究领域**学  神经生物学  Alzheimer's  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量67kDa

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human APPBP2

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-APPBP2/FITC抗体

产品介绍background:

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008].

Function:

May play a role in intracellular protein transport. Anti-APPBP2/FITC抗体May be involved in the translocation of APP along microtubules toward the cell surface.

Subunit:

Binds APP.

Subcellular Location:

Nucleus. Cytoplasm

Post-translational modifications:

Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.

Similarity:

Contains 8 TPR repeats.

Anti-APPBP2/FITC抗体

Entrez Gene: 10513 Human

Entrez Gene: 66884 Mouse

Entrez Gene: 303396 Rat

Entrez Gene: 417645 Chicken

Omim: 605324 Human

SwissProt: Q92624 Human

SwissProt: Q9DAX9 Mouse

SwissProt: A5HK05 Rat

Unigene: 84084 Human

Unigene: 271997 Mouse

Unigene: 104856 Rat

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.