产品名称：Anti-APBB2/FITC抗体

Anti-APBB2/FITC抗体

产品编号YB-11627R-FITC

英文名称Anti-APBB2/FITC

中文名称FITC标记的铁蛋白Fe65样蛋白1抗体

别    名Amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65 like); Amyloid beta A4 precursor protein binding family B member 2; Amyloid beta A4 precursor protein-binding family B member 2; APBB 2; APBB2; APBB2_HUMAN; Fe65 like 1; Fe65 like; Fe65 like protein; FE65L 1; FE65L; FE65L1; Protein Fe65-like 1; Rirl 1; Rirl1; TR2 L; TR2L; Zfra; Zinc finger like protein.

Anti-APBB2/FITC抗体 

说 明 书100ul  

研究领域细胞生物  神经生物学  信号转导  Alzheimer's  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

产品应用ICC=1:50-200 IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量83kDa

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human APBB2

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-APBB2/FITC抗体

产品介绍background:

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Anti-APBB2/FITC抗体Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Function:

May modulate the internalization of beta-amyloid precursor protein.

Subunit:

Anti-APBB2/FITC抗体Binds to the intracellular domain of the beta-amyloid precursor protein.

Similarity:

Contains 2 PID domains.

Contains 1 WW domain.

Database links:

Entrez Gene: 323 Human

Entrez Gene: 11787 Mouse

Omim: 602710 Human

SwissProt: Q92870 Human

SwissProt: Q9DBR4 Mouse

Unigene: 479602 Human

Unigene: 482700 Mouse

Unigene: 5159 Mouse

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.