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Anti-Acrosin/FITC抗体
产品编号YB-5151R-FITC
英文名称Anti-Acrosin/FITC
中文名称FITC标记的精子顶体前体蛋白抗体
别 名ACR; Acrosin precursor; ACRS;Preproacrosin; Proacrosin; ACRO_HUMAN.
Anti-Acrosin/FITC抗体
说 明 书100ul
研究领域细胞生物 **学 泛素
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量2/41/44kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Acrosin
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-Acrosin/FITC抗体
产品介绍background:
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Function:
Acrosin is the major protease of mammalian spermatozoa.Anti-Acrosin/FITC抗体 It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
Subunit:
Heavy chain (catalytic) and a light chain linked by two disulfide bonds. Forms heterodimer with SERPINA5.
Anti-Acrosin/FITC抗体Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Database links:
Entrez Gene: 49 Human
Omim: 102480 Human
SwissProt: P10323 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.