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Anti-APLP2/FITC抗体
产品编号YB8462R-FITC
英文名称Anti-APLP2/FITC
中文名称FITC标记的淀粉样蛋白β前体样蛋白2抗体
别 名amyloid beta (A4) precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.
Anti-APLP2/FITC抗体
说 明 书100ul
研究领域细胞生物 **学 神经生物学 Alzheimer's
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Pig, Horse,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量80kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APLP2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-APLP2/FITC抗体
产品介绍background:
APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Function:
May play a role in the regulation of hemostasis. Anti-APLP2/FITC抗体The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Subunit:
Interacts with CPEB1.
Subcellular Location:
Cell membrane. Nucleus.
Tissue Specificity:
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Post-translational modifications:
The BPTI/Kunitz inhibitor domain is O-glycosylated.
Similarity:
Anti-APLP2/FITC抗体Belongs to the APP family.
Contains 1 BPTI/Kunitz inhibitor domain.
Database links:
Entrez Gene: 334 Human
Entrez Gene: 11804 Mouse
Entrez Gene: 64312 Rat
Omim: 104776 Human
SwissProt: Q06481 Human
SwissProt: Q06335 Mouse
SwissProt: P15943 Rat
Unigene: 370247 Human
Unigene: 19133 Mouse
Unigene: 129285 Rat
Unigene: 1423 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.