产品名称：Anti-APLP2/FITC抗体

Anti-APLP2/FITC抗体

产品编号YB8462R-FITC

英文名称Anti-APLP2/FITC

中文名称FITC标记的淀粉样蛋白β前体样蛋白2抗体

别    名amyloid beta (A4) precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.

Anti-APLP2/FITC抗体

说 明 书100ul  

研究领域细胞生物  **学  神经生物学  Alzheimer's  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Chicken, Pig, Horse,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量80kDa

细胞定位细胞膜

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human APLP2

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-APLP2/FITC抗体

产品介绍background:

APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.

May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

Function:

May play a role in the regulation of hemostasis. Anti-APLP2/FITC抗体The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

Subunit:

Interacts with CPEB1.

Subcellular Location:

Cell membrane. Nucleus.

Tissue Specificity:

Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.

Post-translational modifications:

The BPTI/Kunitz inhibitor domain is O-glycosylated.

Similarity:

Anti-APLP2/FITC抗体Belongs to the APP family.

Contains 1 BPTI/Kunitz inhibitor domain.

Database links:

Entrez Gene: 334 Human

Entrez Gene: 11804 Mouse

Entrez Gene: 64312 Rat

Omim: 104776 Human

SwissProt: Q06481 Human

SwissProt: Q06335 Mouse

SwissProt: P15943 Rat

Unigene: 370247 Human

Unigene: 19133 Mouse

Unigene: 129285 Rat

Unigene: 1423 Rat

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.