产品名称：Anti-AGFG1/FITC抗体

Anti-AGFG1/FITC抗体

产品编号YB8072R-FITC

英文名称Anti-AGFG1/FITC

中文名称FITC标记的艾滋病病毒复制结合蛋白抗体

别    名HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.

Anti-AGFG1/FITC抗体  

说 明 书100ul  

研究领域细胞生物  **学  信号转导  **及病毒  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Horse,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量58kDa

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human AGFG1

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-AGFG1/FITC抗体

产品介绍background:

Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Function:

Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. Anti-AGFG1/FITC抗体This step is essential for HIV-1 replication.

Subunit:

Interacts with EPS15R and EPS15. Interacts with FCHO1.

Subcellular Location:

Nucleus. Cytoplasmic vesicle.

Tissue Specificity:

Ubiquitously expressed.

Post-translational modifications:

O-glycosylated (By similarity).

Similarity:

Anti-AGFG1/FITC抗体Contains 1 Arf-GAP domain.

Database links:

Entrez Gene: 536149 Cow

Entrez Gene: 3267 Human

Entrez Gene: 15463 Mouse

Entrez Gene: 363266 Rat

Omim: 600862 Human

SwissProt: Q2TA45 Cow

SwissProt: P52594 Human

SwissProt: Q8K2K6 Mouse

SwissProt: Q4KLH5 Rat

Unigene: 352962 Human

Unigene: 392569 Mouse

Unigene: 433409 Mouse

Unigene: 3734 Rat

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.