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Anti-ATE1/FITC抗体
产品编号YB-7973R-FITC
英文名称Anti-ATE1/FITC
中文名称FITC标记的精氨酸tRNA的蛋白转移酶1抗体
别 名Arginine tRNA protein transferase 1; Arginyl-tRNA--protein transferase 1; Arginyl-tRNA-protein transferase; Arginyltransferase 1; R transferase 1; EC 2.3.2.8; AI225793; ATE1_HUMAN.
Anti-ATE1/FITC抗体
说 明 书100ul
研究领域细胞生物 **学 转录调节因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量59kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ATE1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-ATE1/FITC抗体
产品介绍background:
ATE1, also known as arginyltransferase 1, is an enzyme that is involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. There are two named isoforms.
Function:
Involved in the post-translational conjugation ofarginine to the N-terminal aspartate or glutamate of a protein.Anti-ATE1/FITC抗体This arginylation is required for degradation of the protein viathe ubiquitin pathway. Does not arginylate cysteine residues (Bysimilarity).
Subunit:
Monomer (Potential).
Subcellular Location:
Isoform ATE1-1: Nucleus (By similarity).Cytoplasm (By similarity).
Isoform ATE1-2: Cytoplasm (By similarity).
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Anti-ATE1/FITC抗体Similarity:
Belongs to the R-transferase family.
Database links:
UniProtKB/Swiss-Prot: O95260.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.