产品名称：Anti-ABHD13/FITC抗体

Anti-ABHD13/FITC抗体

产品编号YB-7943R-FITC

英文名称Anti-ABHD13/FITC

中文名称FITC标记的水解酶结构域蛋白13抗体

别    名ABHD13; ABHDD_HUMAN; abhydrolase domain containing 13; Abhydrolase domain-containing protein 13; BEM46L1; C13orf6.

Anti-ABHD13/FITC抗体

说 明 书100ul  

研究领域细胞生物  **学  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish, Sheep,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量39kDa

细胞定位细胞膜

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ABHD13

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year.Anti-ABHD13/FITC抗体 Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-ABHD13/FITC抗体

产品介绍background:

The alpha/beta hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical alpha/beta hydrolase fold, which consists of an eightstranded parallel alpha/beta structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer’s disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members. Most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD13 is a 337 amino acid single-pass membrane protein that belongs to the ABHD family.

Subcellular Location:

Membrane; Single-pass type II membrane protein (Potential).

Similarity:

Belongs to the serine esterase family.

Anti-ABHD13/FITC抗体Database links:

Entrez Gene: 84945 Human

Entrez Gene: 68904 Mouse

Entrez Gene: 306630 Rat

Entrez Gene: 561333 Zebrafish

SwissProt: Q7L211 Human

SwissProt: Q80UX8 Mouse

SwissProt: Q32LS6 Zebrafish

Unigene: 183528 Human

Unigene: 142570 Mouse

Unigene: 395885 Mouse

Unigene: 88157 Zebrafish

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.