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Anti-ABCA9/FITC抗体
产品编号YB-7853R-FITC
英文名称Anti-ABCA9/FITC
中文名称FITC标记的三磷酸腺苷结合盒转运蛋白9抗体
别 名ATP binding cassette A9; ATP binding cassette sub family A (ABC1) member 9; ATP binding cassette sub family A member 9; DKFZp686F2450; EST640918; MGC75415; ABCA9_HUMAN.
Anti-ABCA9/FITC抗体
说 明 书100ul
研究领域细胞生物 **学 信号转导 细胞周期蛋白 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Horse,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量184kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ABCA9
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-ABCA9/FITC抗体
产品介绍background:
ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA9 is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of the ABCA9 gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. Anti-ABCA9/FITC抗体ABCA9 May play a role in monocyte differentiation and lipid homeostasis.
Function:
May play a role in monocyte differentiation and lipidhomeostasis.
Subcellular Location:
Membrane; Multi-pass membrane protein(Potential).
Tissue Specificity:
Widely expressed with higher expression inheart.
Anti-ABCA9/FITC抗体Similarity:
Belongs to the ABC transporter superfamily. ABCAfamily.
Contains 2 ABC transporter domains.
Database links:
Entrez Gene: 10350 Human
Entrez Gene: 217262 Mouse
Entrez Gene: 287788 Rat
Omim: 612507 Human
SwissProt: Q8IUA7 Human
SwissProt: Q8K449 Mouse
Unigene: 131686 Human
Unigene: 291459 Mouse
Unigene: 98251 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.