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Anti-ALOXE3/FITC抗体
产品编号YB-7856R-FITC
英文名称Anti-ALOXE3/FITC
中文名称FITC标记的表皮型脂氧合酶3抗体(鱼鳞病相关蛋白)
别 名ALOXE3; Arachidonate lipoxygenase 3; e LOX 3; E LOX; e-LOX-3; eLOX3; Epidermal lipoxygenase; Epidermis-type lipoxygenase 3; Lipoxygenase 3; LOXE3_HUMAN.
Anti-ALOXE3/FITC抗体
说 明 书100ul
研究领域细胞生物 信号转导 细胞周期蛋白 细胞分化 细胞类型标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量81kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALOXE3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-ALOXE3/FITC抗体
产品介绍background:
Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known. Tissue specificity:Predominantly expressed in skin. Involvement in diseaseDefects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE). NCIE is a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affected individuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membrane subsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than in lamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. In contrast to lamellar ichthyoses, scales are usually white, Anti-ALOXE3/FITC抗体fine and powdery, and palms and soles are severely affected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and loss of pulp volume.
Tissue Specificity:
Predominantly expressed in skin.
Similarity:
Belongs to the lipoxygenase family. Contains 1 lipoxygenase domain. Contains 1 PLAT domain.
Anti-ALOXE3/FITC抗体Database links:
Entrez Gene: 59344 Human
Entrez Gene: 23801 Mouse
Entrez Gene: 287424 Rat
Omim: 607206 Human
SwissProt: Q9BYJ1 Human
SwissProt: Q9WV07 Mouse
Unigene: 232770 Human
Unigene: 41989 Mouse
Unigene: 8716 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.