产品名称：Anti-ANGPTL6/FITC抗体

Anti-ANGPTL6/FITC抗体

产品编号YB-7027R-FITC

英文名称Anti-ANGPTL6/FITC

中文名称FITC标记的血管生成素相关蛋白6抗体

别    名ARP5; AGF; Angiopoietin like 6; Angiopoietin like Protein 6; Angiopoietin related Growth Factor; Angiopoietin related protein 5; Angiopoietin-like protein 6; Angiopoietin-related growth factor; Angiopoietin-related protein 5; Angiopoietin-related protein 6; ANGL6_HUMAN; Angptl6; ARP5.

Anti-ANGPTL6/FITC抗体

说 明 书100ul  

研究领域心血管  细胞生物  血管内皮细胞  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Horse, Sheep,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量49kDa

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ANGPTL6

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-ANGPTL6/FITC抗体

产品介绍background:

Angptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract obesity by increasing energy expenditure. Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

Function:

May play a role in the wound healing process.Anti-ANGPTL6/FITC抗体 May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.

Subcellular Location:

Secreted (Probable).

Similarity:

Contains 1 fibrinogen C-terminal domain.

Database links:

Entrez Gene: 83854 Human

Anti-ANGPTL6/FITC抗体Entrez Gene: 70726 Mouse

Omim: 609336 Human

SwissProt: Q8NI99 Human

SwissProt: Q8R0Z6 Mouse

Unigene: 712850 Human

Unigene: 34019 Mouse

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.