产品名称：Anti-Acid Phosphatase/FITC抗体

Anti-Acid Phosphatase/FITC抗体

产品编号YB-6291R-FITC

英文名称Anti-Acid Phosphatase/FITC

中文名称FITC标记的酸性磷酸酶抗体

别    名Acid phosphatase 1 soluble; Acid phosphatase of erythrocyte; Adipocyte acid phosphatase; Cytoplasmic phosphotyrosyl protein phosphatase; HAAP; Low molecular weight phosphotyrosine protein phosphatase; PAP1; PAP2; Protein tyrosine phosphatase; PTPase; Purple acid phosphatase; Red cell acid phosphatase 1; PPAC_HUMAN.

Anti-Acid Phosphatase/FITC抗体

说 明 书100ul  

研究领域肿瘤  细胞生物  细胞周期蛋白  激酶和磷酸酶  肿瘤细胞生物标志物  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量18kDa

性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Acid Phosphatase

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-Acid Phosphatase/FITC抗体

产品介绍background:

Phosphatase enzymes catalyse hydrolysis of phosphoric acid esters of various alcohols, e.g. a hexose phosphate, to yield the alcohol and free inorganic phosphate. This may be a way of recycling phosphate in the cell, and the level of phosphate may be elevated under conditions of phosphate starvation (in algae for example). Acid phosphatases have pH optima below 7, whereas alkaline phosphatases are most active above pH 7. Commercial quantities of acid phosphatase are obtained from plant sources e.g.Anti-Acid Phosphatase/FITC抗体 potato and wheat germ, whereas similar quantities of alkaline phosphatase are obtained from animal intestine and bacteria.

Function:

Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.

Subunit:

Isoform 1 interacts with the SH3 domain of SPTAN1. There is no interaction observed for isoforms 2 or 3. Interacts with EPHA2; dephosphorylates EPHA2. Interacts with EPHB1.

Subcellular Location:

Anti-Acid Phosphatase/FITC抗体Cytoplasm.

Tissue Specificity:

T-lymphocytes express only isoform 2.

Similarity:

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Database links:

UniProtKB/Swiss-Prot: P24666.3

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.