产品名称：Anti-Omgp/FITC抗体

Anti-Omgp/FITC抗体

产品编号YB-1200R-FITC

英文名称Anti-Omgp/FITC

中文名称FITC标记的少突细胞髓磷脂糖蛋白抗体

别    名olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN.  

Anti-Omgp/FITC抗体

说 明 书100ul  

研究领域神经生物学  信号转导  细胞凋亡  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应 Human, Mouse, Rat, Cow,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量43kDa

Anti-Omgp/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Omgp

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-Omgp/FITC抗体

产品介绍background:

Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin.

Function:

Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

Subunit:

Binds to RTN4R.

Subcellular Location:

Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:

Oligodendrocytes and myelin of the central nervous system.

Anti-Omgp/FITC抗体Post-translational modifications:

O-glycosylated in its Ser/Thr-rich repeat domain (Potential).

Similarity:

Contains 8 LRR (leucine-rich) repeats.

Contains 1 LRRNT domain.

Database links:

Entrez Gene: 407186 Cow

Entrez Gene: 4974 Human

Entrez Gene: 100172122 Orangutan

Omim: 164345 Human

SwissProt: P23515 Human

Unigene: 113874 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OMgp也是髓鞘糖蛋白的一种，在发育期促进轴突生长,成熟期抑制轴突生长.其抑制作用主要由髓鞘来源的抑制分子的共同受体NgR介导,在神经营养因子受体p75NTR以及小GTP酶Rho等信号分子的共同参与下完成.