产品名称：Anti-GIP/FITC抗体

Anti-GIP/FITC抗体

产品编号YB0098R-FITC

英文名称Anti-GIP/FITC

中文名称FITC标记的胃泌素抑制肽抗体

别    名Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic polypeptide; Incretin hormone.  

Anti-GIP/FITC抗体

说 明 书100ul  

研究领域信号转导  生长因子和**  转录调节因子  糖尿病  

抗体来源Rabbit

克隆类型Polyclonal

交叉反应 Human, Mouse, Rat, Pig, Cow,

产品应用IF=1:50-200  

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量16kDa

Anti-GIP/FITC抗体性    状Lyophilized or Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human GIP

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-GIP/FITC抗体

产品介绍background:

GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 Anti-GIP/FITC抗体amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion.

Function:

Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.

Subcellular Location:

Secreted.

Similarity:

Belongs to the glucagon family.

Database links:

Entrez Gene: 2695 Human

Omim: 137240 Human

SwissProt: P09681 Human

Unigene: 1454 Human

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胃泌素抑制肽（GIP）是胃肠道的一种由42个氨基酸组成的多肽**，又称为葡萄糖依赖性促胰岛素多肽（glucose-dependent insulinotropic peptide，GIP）他强烈抑制胃分泌和运动，也可调节胰岛素的释放。GIP属于Glucagon家族成员